If you’re searching for information about 116 Lewis St, San Antonio, TX, you may notice that the property appears in several public records with different classifications. This has led many people to wonder whether the address is a residence, a medical office, or another type of business. Based on publicly available information, the property has primarily been associated with healthcare services while also being listed as commercial real estate.
A Healthcare Practice Address
The most notable use of 116 Lewis St, San Antonio, TX 78212 is as a registered practice location in the National Plan and Provider Enumeration System (NPPES) NPI Registry. The NPI Registry is a federal database maintained by the Centers for Medicare & Medicaid Services (CMS) that records healthcare providers and their practice locations.The listing indicates that the address has been used as a practice location for an individual healthcare provider. However, a practice address does not necessarily mean the entire building is occupied by a medical business. In many cases, healthcare professionals use office spaces within mixed-use properties.
Real Estate Classification
Commercial real estate websites provide additional insight into the property’s characteristics. According to listings from platforms such as LoopNet, the building is described as a medical office/commercial property. These listings suggest that the property is suitable for professional offices, particularly healthcare-related businesses.Meanwhile, residential real estate websites like Zillow and Realtor.com have also identified the building as a single-family residence or a property with residential features. This difference is common for older buildings that have been adapted for commercial or professional use over time.
Property Features
Public real estate records describe the property as:
- Approximately 2,084 square feetLocated in the historic Tobin Hill neighborhoodSuitable for either residential or commercial use depending on zoning and occupancyPreviously marketed as a medical office or professional workspace
Its location near downtown San Antonio makes it attractive for healthcare providers, attorneys, consultants, and other professional businesses.
Why the Property Has Multiple Classifications
The varying descriptions of the property are not unusual. Many historic properties in San Antonio serve multiple purposes throughout their lifetime. A building may be:
- Originally constructed as a private homeConverted into professional office spaceRegistered as a healthcare provider’s practice addressListed for sale as either residential or commercial real estate
Because of these transitions, different databases may display different property types based on their own records.
Is There a Specific Business at 116 Lewis St?
Public records primarily identify the location as a healthcare provider’s registered practice address rather than a large commercial business or retail establishment. The available information does not indicate that the address serves as the headquarters of a widely recognized company. Instead, it appears to function as a professional office used by an individual healthcare practitioner.
Final Thoughts
Based on publicly available records, 116 Lewis St, San Antonio, TX is best described as a property that has been used as an individual healthcare provider’s practice location while also being recognized by commercial real estate platforms as a medical office/commercial property. Some real estate databases continue to classify it as a single-family residence, reflecting the building’s mixed-use history and adaptable design.
Anyone seeking the property’s current occupant or business should verify the latest information through official local business records or the most recent NPI Registry and property listings, as occupancy and business use may change over time.

